Boehringer Ingelheim files BLA for antidote to dabigatran

02.03.20151466
Boehringer Ingelheim announced that it has submitted a biologics license application to the FDA requesting an accelerated approval pathway for idarucizumab, an antidote to dabigatran.

Serious cardiac complications in coronary spasm provocation tests using acetylcholine or ergonovine: analysis of 21 512 patients from the diagnosis procedure combination database in Japan

28.02.20151649
This retrospective cohort study suggested that acetylcholine (ACH) tests were associated with a higher rate of cardiac complications than ergonovine (ER) tests.

Statin use may reduce risk for liver cancer

27.02.20151405
The use of statins decreased the risk for primary liver cancer, especially in patients with liver disease and diabetes, according to newly published data.

Larger and more severe strokes seen with aspirin resistance

25.02.20151825
Patients with acute ischemic stroke who test positive for aspirin resistance had both larger stroke volume and increased severity, compared with patients without resistance, in an observational study of 311 patients at Korean centers.

Concomitant NSAIDs with antithrombotic therapy after MI worsen outcomes

24.02.20151546
In a study of patients assigned antithrombotic therapy after MI, concomitant use of nonsteroidal anti-inflammatory drugs were associated with increased risk for bleeding and excess thrombotic events, regardless of treatment duration.

ICD benefit persists with increasing patient age

20.02.20151448
The survival benefit conferred by implantable cardioverter-defibrillators (ICDs) persists with increasing patient age.

Odds of major bleeding, mortality lower with fondaparinux than heparin

19.02.20151420
Patients with non-STEMI who were treated with fondaparinux had better rates of major bleeding and mortality during hospitalization and up to 180 days after discharge compared with patients treated with low–molecular-weight heparin, according to new data.
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